About

Hi! I'm Santhilal Subhash

Keen to address molecular mechanisms involved in tumorigenesis by integrating datasets from different high- throughput techniques – By analyzing genome-wide chromatin profiles, I have predicted possible mechanisms of active and inactive chromatin-associated RNA molecules – From integrative approach using chromatin and transcriptome datasets of mammalian gametes, developmental stages, somatic, and cancer tissues, I identified a unique set of sperm-specific lincRNAs – In addition to that, using transcriptome and methylome datasets from The Cancer Genome Project (TCGA) PAN-cancer dataset, I have identified cell cycle associated functional RNA molecules having a role as an oncogene and tumor suppressors in multiple cancers – Overall my interest is to integrated transcriptome- and chromatin-based high-throughput datasets to find RNA molecule-based biomarkers in cancer and other diseases that can be used for future therapeutics.

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Contact me here!

Email: santhilal.subhash@ki.se

Phone: +46-(0)8-524 810 66

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Profile

Addressing problems in molecular biology using different computational and statistical approaches.

My research focus is on epigenetics using RNA-seq/ChIP/RIP/HiC/MEDIP/Methyl-seq data from different cancers cell lines and patients. Also developing pipelines or softwares related to functional genomics.

Name: Santhilal Subhash

Address: Blickagången 16, 14152, Flemmingsberg, Stockholm, Sweden

Phone: +46-(0)8-524 810 66

Current position: Postdoctoral Researcher

Lab: Prof. Maria Eriksson Laboratory

Experience

Postdoctoral Researcher (Prof. Eriksson's lab) - Karolinska Institute

Stockholm - Sweden

2020 - Present

Ph.D. Student (Medical science, Prof. Kanduri's lab) - University of Gothenburg

Gothenburg - Sweden

2014 - 2020

Research assistant (Bioinformatics, Prof. Kanduri's lab) - University of Gothenburg

Gothenburg - Sweden

2012 - 2014

Project student (Bioinformatics, prof. Larsson's lab) - University of Gothenburg

Gothenburg - Sweden

2011 - 2012

Education

Ph.D. in Medical Science (Computational biology) - University of Gothenburg

Gothenburg - Sweden

2014 - 2020

Bachelor of Technology in Bioinformatics - SRM University

Chennai - India

2004 - 2008

Secondary school education - Sri Vidya Mandir Higher Sceondary School

Thirukovilur - India

2002 - 2004

Primary school education - Sri Vidya Mandir School

Thirukovilur - India

1990 - 2001

Applied Skills in my reseach

Transcriptome analysis

90%

Genome analysis

75%

Chromatin profiling

60%

Methylation analysis

50%

Tools/pipelines

40%

Programming/scripting

40%